SubB2M Platform

SubB2M is an engineered protein that specifically detects the cancer biomarker neu5Gc that is found in multiple human cancers. INOVIQ is developing simple, affordable and more accurate SubB2M-based blood tests for cancer detection and monitoring.


Scientific Rationale

Cancer cells have a distinct feature of adding different sugar molecules to the proteins they produce, which sets them apart from normal cells.

One such sugar molecule commonly found in cancer cells is Neu5Gc. SubB2M preferentially binds to Neu5Gc. SubB2M is a promising multicancer probe. Incorporating SubB2M into existing cancer diagnostic tests, may improve their sensitivity and specificity in detecting various types of cancer.